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Oren Milstein, PhD

Oren Milstein, PhD

Patent Agent, Herzliya

   Contact information

  • +972-9-972-8217

Admitted

  • U.S. Patent & Trademark Office

Education

Weizmann Institute of Science, Ph.D. Life Sciences, 2008
Weizmann Institute of Science, M.Sc. Life Sciences, 2002
The Hebrew University, B.Sc. Animal Science, 2000 

About Oren Milstein, PhD

Oren Milstein is admitted to practice before the U.S. Patent and Trademark Office. His practice focuses on patent matters in the biotechnology, medical device and pharmaceutical industries. Oren is an established entrepreneur, having founded a start-up company based on one of his inventions.

As a scientist, Oren has more than 10 years of research experience in the Life Sciences.  He received his Ph.D. in Immunology from The Weizmann Institute of Science in 2008, where in collaboration with NYU he deciphered key elements in T cell activation and developed novel strategies for successful bone marrow transplantation into irradiated subjects.Subsequently, as an NIH Fellow at The Scripps Research Institute, Oren performed his postdoctoral research in the laboratory of Nobel Prize Laureate Dr. Bruce Beutler. There, he discovered a novel mechanism for iron deficiency anemia leading to a publication which challenges our understanding of the impact of antacids on iron absorption. Until recently, Oren served as Adjunct Professor of Immunology at Mount St. Mary’s College in Los Angeles. His research has resulted in several peer-reviewed publications and patents. 

Languages

English & Hebrew

Publications

Milstein, O., Kreig L., Krebs, P., Beutler B., Du, X. (2011) Mutation of the gastric hydrogen-potassium ATPase alpha subunit causes iron deficiency anemia in mice. Blood. 2011 Dec 8; 118 (24):6418-25.

Lask, A., Goichberg P., Goren-Arbel R., Milstein O., Aviner S., Feine I. , Klein T., Berrebi, A., and Reisner, Y (2011) TCR independent killing of B cell malignancies by anti-3rd party CTLs: The critical role of MHC-CD8 engagement J Immunol.; 187(4):2006-14.

Milstein, O., Hagin, D., Lask, A., Reich-Zeliger, S., Shezan E., Ophir E., Eidelshtein Y., Afik R., Antebi YE., Dustin ML. and Reisner Y. (2011) CTLs respond with activation and granule secretion when serving target for T cell recognition. Blood 117,1042-1052

Tchorsh-Yutsis D, Hecht G, Aronovich A, Shezen E, Klionsky Y, Rosen C, Bitcover R, Eventov-Friedman S, Katchman H, Cohen S, Tal O, Milstein O, Yagita H, Blazar BR, Reisner Y. (2009). Pig embryonic pancreatic tissue as a source for transplantation in diabetes: transient treatment with anti-LFA1, anti-CD48, and FTY720 enables long-term graft maintenance in mice with only mild ongoing immunosuppression. Diabetes 58, 1585-94

Milstein, O., S.Y. Tseng, T. Starr, J. Llodra, A. Nans, M. Liu, M.K. Wild, P.A. van der Merwe, D.L. Stokes, Y. Reisner, and M.L. Dustin. (2008). Nanoscale increases in CD2-CD48 mediated intermembrane spacing decrease adhesion and reorganize the immunological synapse. J Biol Chem. 283, 34414-22.

Dekel, B., Burakova, T., Arditti, F. D., Reich-Zeliger, S., Milstein, O., Aviel-Ronen, S., Rechavi, G., Friedman, N., Kaminski, N., Passwell, J. H., and Reisner, Y. (2003). Human and porcine early kidney precursors as a new source for transplantation. Nature Med 9, 53-60.

Katz, U., Bracha, R., Nuchamowitz, Y., Milstein, O., and Mirelman, D. (2003). Comparison between constitutive and inducible plasmid vectors used for gene expression in Entamoeba histolytica. Mol Biochem Parasitol 128, 229-233.