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Dror Shiftan, Ph.D.

Dror Shiftan, Ph.D.

Patent Attorney, Herzliya

   Contact information

  • +972-9-972-8042

Admitted

  • Israel Patent Office

Education

McGill University, Post-Doctoral Fellowship (Chemistry), 2000

Ben-Gurion University of the Negev, M.S. and Ph.D. (Chemistry), 1998

Ben-Gurion University of the Negev, B.Sc. (Chemistry), 1992

About Dror Shiftan, Ph.D.

Dror is a Patent Attorney in the Patents and Life Sciences Groups of PCZL’s Herzliya office. Dror’s experience as a scientific advisor and as an Israeli patent attorney encompasses the areas of pharmaceuticals, chemistry, and biology. Dror has also handled intellectual property matters ranging from patent prosecution to non-infringement and invalidity opinions involving pharmaceutical formulations, active compounds, and processes for preparing active compounds.

Dror is highly experienced in solving the three-dimensional structure of molecules, liquid and solid-state NMR, computer modeling and X-ray analysis, medicinal chemistry and rational drug design, polymer chemistry, and polymers as excipient for drug delivery.

Languages

English & Hebrew

Publications

Glaser R, Shiftan D, Drouin M. Eight-membered ring conformations: The interconvertion of the solid-state conformations of retronefopam hydrochloride and deoxynefopam hydrochloride into those exhibited by nefopam hydrochloride, a non-narcotic analgestic drug. New J Chem. 1994;18:973. 

Glaser R, Shiftan D, Drouin M. The stereochemistry of a nine-membered ring analogue of nefopam, a non-narcotic analgestic drug. Struct Chem. 1995;6(1):25-35.

Glaser R, Adin I, Shiftan D, Shi Q, Deutsch HM, Wu KM, Froimowitz M. Solution and solid-state conformational and structural analysis of the n-methyl derivatives of (+/-)-threo-methylphenidate, (+/-)-erythro-methylphenidate, and (+/-)-threo-p-methyl-methylphenidate hydrochloride salts. J Org Chem. 1998;63(6):1785-94.

Glaser R, Shiftan D. The stereochemistry and interconvertion of nine-membered rings containing one strong torsional constraint. Adv Mol Struct Res. 1999;5:89-151.

Glaser R, Shiftan D, Drouin M. Conformational pseudopolymorphism and solid-state CPMAS NMR studies for determination of solvent-dependent solution-state conformational preferences for (-)-scopolamine hydrobromide/hydrochloride salts. J Org Chem. 1999;64(25):9217-24. (Additions and corrections: ibid. 2000;65:1898).

Glaser R, Shiftan D, Froimowitz M. NMR structure determination of brefeldin-A, a 13-membered ring fungal metabolite. Magn Reson Chem. 2000;38(4):274-80.

Glaser R, Shiftan D, Drouin M. The solid-state structures of (-)-scopolamine free base, (-)-scopolamine methobromide, (-)-scopolamine hydrobromide trihydrate, and of the pseudopolymorphic forms of (-)-scopolamine hydrochloride anhydrate and 1.66hydrate. Can J Chem. 2000;78:212-3.

Lebail P, Buleon A, Shiftan D, Marchessault RH. Mobility of lipis in complexes of amylose-fatty acids by deuterium and 13C solid-state NMR. Carbohydrates Polymers. 2000;43:317-26.

Shiftan D, Ravenelle F, Mateescu MA, Marchessault RH. Change in the V/B polymorph ratio and T1 relaxation of epichlorohydrin crosslinked high amylose starch. Starch. 2000;52:186-95.

Glaser R, Novoselsky A, Shiftan D. Eight-membered-ring solid-state conformational interconversion via the atom-flip mechanism, a CPMAS 13C NMR and crystallographic stereochemical study. J Org Chem. 2000;65:6345-53.

Glaser R, Shiftan D, Levi-Roso G, Ergaz I, Geresh S, Drouin M. cis-Cyclononene conformational families and a crystallographic example of a skew-chair[bond]boat type-2 conformation. J Org Chem. 2002;67:5486-96.

Co-developer and co-author of first Drug Design courseware, Molecular Conceptor Learning Series, at http://www.drugdesign.com/web/ (Version 1, 2002 and Version 2, 2004).

Practice areas

Industries